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영남의대학술지 Vol.24_No.2 Suppl. P.S627-631, Dec. 2007

Case Report

혈청 아밀라제 및 리파제가 정상인 급성 췌장염 1 예

Normal Amylase and Lipase Serum Level in Acute Pancreatitis: A Case Report

영남대학교 의과대학 소아과학교실
책임저자:최광해, 대구광역시 남구 대명5동 317-1, 영남대학교 의과대학 소아과학교실
Tel: (053) 620-3536, Fax: (053) 629-2252
E-mail: ckh@med.yu.ac.kr

December 30, 2007


Acute pancreatitis is an inflammatory disease of pancreas which comes from various etiologies. The pathologic spectrum of acute pancreatitis varies from mild edematous pancreatitis to severe necrotizing pancreatitis. Diagnosis of acute pancreatitis relies on clinical symptoms and increase of serum lipase and amylase within 48 hours. We report the case of a patient admitted in the pediatric department with about 24 hour history of acute abdominal pain. A computed tomography scan revealed an acute pancreatitis in spite of the serum amylase and lipase level being normal.

Key Words: Normal amylase, Normal lipase, Acute pancreatitis


1. French Consensus Conference on Acute Panc- reatitis: Conclusions and Recommendations. Paris, France, 25?26 January 2001. Eur J Gastroenterol Hepatol 2001 Dec;13(Suppl 4):S1-13.

2. Lim DH, Jo WJ, Park CH, Pai ST. A clinical study on acute pancreatitis. Korean J Gastroe- nterol 1993 Apr;25(2):363-8.

3. Ju KJ, Suh DH, Kim CS, Lee CH, Shim YW, Song KY. The clinical observation of acute pancreatitis. Korean J Gastroenterol 1994 Dec; 26(6):995-1001.

4. Lim YS, Ryu JK, Lee HC, Kim YT, Yoon BY, Kim CY. Comparison of etiological and prognostic factor in acute necrotizing pancreatitis. Korean J Gastroenterol 1997 May;29(5):667-76.

5. 안효섭. 홍창의 소아과학. 제 9판. 서울: 대한교과서(주), 2007;574-5

6. Ballinger AB, Barnes E, Alstead EM, Fairclough PD. Is intervention necessary after a first episode of acute idiopathic pancreatitis? 1996 Feb;38(2):293-5.

7. Steer ML. Pathogenesis of acute pancreatitis. Digestion 1997;58(suppl 1):46-9.

8. Agarwal N, Pitchumoni CS, Sivaprasad AV. Evaluating tests for acute pancreatitis. Am J Gastroenterol 1990 Apr;85(4):356-66.

9. Khan FY, Matar I. Chylous ascites secondary to hyperlipidemic pancreatitis with normal serum amylase and lipase. World J Gastroenterol. 2007 Jan 21;13(3):480-2.

10. Cartier T, Sogni P, Perruche F, Meyniard O, Claessens YE, Dhainaut JF, Der Sahakian G. Normal lipase serum level in acute pancreatitis: a case report. Emerg Med J. 2006 Sep;23(9): 701-2.

11. Orebaugh SL. Normal amylase levels in the presentation of acute pancreatitis. Am J Emerg Med. 1994 Jan;12(1):21-4.

12. Otusbo S, Huruzono T, Kobae H, Yoshimi S, Miyata K. Pancreatitis with normal serum amylase associated with sodium valproate: a case report. Brain Dev. 1995 May-Jun;17(3): 219-21.

13. Ruzena S. Normal serum amylase in acute pancreatitis. Dig Dis Sci. 1989 Jun;34(6):960-1.

14. Okerberg K, Lee M. Spuriously normal amylase levels in a patient with acute pancreatitis secondary to hypertriglyceridemia. J Am Board Fam Pract. 1999 Jan-Feb;12(1):68-70.