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영남의대학술지 Vol.24_No.2 Suppl. P.S330-339, Dec. 2007

Original Article

폐경 전 여성의 골감소증 관련요인

Factors Affecting Bone Mineral Density in Premenopausal Women

이명숙, 강복수*, 이경수*
영남대학교 환경보건대학원,
영남대학교 의과대학 예방의학교실*
책임저자:강복수, 대구광역시 남구 대명5동 317-1, 영남대학교 의과대학 예방의학교실
Tel: (053) 620-4372, Fax: (053) 653-2061
E-mail: pskang@ynu.ac.kr

December 30, 2007

Abstract

Purpose:The purpose of the study was to determine factors affecting bone mineral density among premenopausal women aged over 45 years old and make a contribution to preventing osteoporosis among postmenopausal women.
Materials and Methods:A total of 133 women enrolled in the study and completed a self-administered questionnaire that measured results of bone mineral density exam and biochemical exam, demographic characteristics, smoking and drinking, physical activities and reproductive characteristics.
Results:The results of the study are summarized as follows: Of total subjects, 20.2% showed a reduction on bone mineral density. Age was the most important factor predicting bone mineral density level. A frequent intake of meat rather than vegetables had a significant impact on bone mineral density. Women with a menstruation cycle shorter than 28 days showed significantly high bone mineral density. Multiple regression analysis revealed a correlation between age and risk of osteoporosis. The explainability for variables was 16%.
Conclusion:It is necessary to develop programs designed to help women in their 30s to maintain the maximum bone density and prevent osteoporosis after menopause.

Key Words: Bone Mineral Density, Premenopausal, Women

References

1. WHO: Prevention and management of osteo- porisis. Technical Report Series 2003;921:1-5.

2. Cooper C, Atkinson EJ, O'Fallon WM, Melton LJ 3rd. Incidence of clinically diagnosed vertebral fractures: a population-based study in Rochester, Minesota, 1985-1989. J Bone Miner Res 1992 Feb ;7(2):221-7.

3. 이종석, 백지선, 구은주, 배철영, 신동학. 폐경기 여성의 골다공증에 관한 조사. 가정의학회지 1994 Mar;157:113-20.

4. Yim MJ, Kyung NH, Han IG. The study of the exercise prescription for increasing bone density in 20-60's women. Kor J Gerontol 1995 Mar;5(1):30-4.

5. Choi KH, Han IK. Standardization for dual anergy X-ray absorptiometry in Korean postmenopausal women according to their lumbar and proximal femur bone mineral density. J Korean Soc Menopause 2000 Apr; 6(1):31-5.

6. 김혜완. 골밀도 검사에서 골다공증의 관련인자에 대한 분석 연구 [석사학위논문]. 경희대학교 대학원; 1999.

7. 박소영. 폐경여성 생식관련요인과 생활양식이 골밀도에 미치는 영향 [석사학위논문]. 대전대학교 보건대학원; 2004.

8. Hunt IF, Murphy NJ, Clark VA, Judd HL, Cedars MI, Browdy BL. Bone mineral content in postmenopausal women, calcium intake early in life, and estrogen therapy. Nutr Res 1990 Oct ;10(10):1061-71.

9. Alekel L, Clasey JL, Fehling PC, Weigel RM, Boileau RA, Erdman JW et al. Contributions of exercise, body composition, and age to bone mineral density in premenopausal women. Med Sci Sports Exerc 1995 Nov ;27(11):1477-85.

10. Alekel DL, Mortillaro E, Hussain EA, West B, Ahmed N, Peterson CT et al. Lifestyle and biologic contributors to proximal femur bone mineral density and hip axis length in two distinct ethnic groups of premenopausal women. Osteoporosis International, 1999;9(4):327-38.

11. Elisman JA, Kelly PJ, Morrison NA, Pocock NA, Yeoman R, Birmingham J et al. Peak bone mass and osteoporosis prevention. Osteoporosis International 1993 Jan;3(1):56-60.

12. Jamal SA, Ridout R, Chase C, Fielding L, Rubin LA, Hawker GA. Bone mineral density and osteoporosis education improve lifestyle behaviors in premenopa usal women. J Bone Min Res 1999 Dec;14(12):2143-9.

13. Fox KM, Magaziner J, Sherwin R, Scott JC, Plato CC, Nevitt M et al. Reproductive correlates of bone mass in elderly women. Study of osteoporotic fractures research group. J Bone Miner Res 1993 Aug;8(8):901-8.

14. Zhang Y, Liu P, Deng H. The impact of reproductive and mentral histiry on bone mineral density in Chinese women. J Clin Densitom 2003 Sep;6(3):289-96.

15. 장숙랑, 최영호, 최문기, 강성현, 정진영, 최용준 등. 춘천지역 폐경후 여성 골다공증 유병율과 관련요인. 예방의학회지 2006 Sep;39(5):389-96.

16. Cosensus Development Conference. Prophylaxis and treatment of osteoporosis. Am J Med 1991 Jan;90(1):107-10.

17. 권재희. 폐경 여성의 골밀도 : 자연 폐경 군과 수술적 폐경 군간의 비교 [석사학위논문]. 서울대학교 대학원; 2000.

18. 임수, 신찬수, 김기수, 김수연. 농촌지역 50세 이상 남녀 인구에서의 요골(radius)과 종골(calcaneus)의 골밀도 결정인자. 대한내분비학회지 2003 Apr;18(2):193-205.

19. Newton-John HF, Morgan DB. The loss of bone with age, osteoporosis, and fractures. Clin Orthop Relat Res. 1970;71:229-52.

20. Krolner B. Lumbar spine bone mineral content by photon beam absorptiometry. Methodology and application in osteoporosis. Dan Med Bull 1985 Jun ;32(3):152-70.

21. Lanyon LE, Rubin CT, O’connor JA, Goodship AE. The Stimulus for mechanically adaptive bone remodeling. Chap in Osteoporosis. Edited by Menczel J, Makin RM, Steinburg J. New York Wilet;1982. p.135-48.

22. McGraw RL, Riggs JE. Osteoporosis, sedentary life style, and increasing hip fractures: pathogenic relationship or differential survival bias. Calcified Tissue International 1994 Aug; 55(2):87-9.

23. Kanders B, Dempster DW, Lindsay R. Interaction of calcium nutritio and physical activity on bone mass in young women. J Bone Min Res 1988 Apr;3:145-9.

24. 배성욱. 폐경 전후 여성의 골 밀도에 영향을 미치는 요인 [석사학위논문]. 경산대학교 보건대학원; 2002.

25. Massey LK, Whiting SJ. Caffeine, urinary calcium, calcium metabolism and bone. Jounal of Nutrition 1993 Sep;123(9):1611-4.

26. 임승길, 정현철, 이미경, 김현만, 이현철, 허갑범. 한국여성 골조송증 환자들에서 보인 골조송증위험인자(예보). 대한내과학회지 1988 Apr;332: 444-51.

27. 박미혜. 폐경기 여성에서 골다공증 위험인자 [석사학위논문]. 이화여자대학교 대학원; 1995.

28. 우선옥, 배상수, 김동현. 한국여성의 골다공증의 위험요인에 관한 환자-대조군 연구. 예방의학회지 1995 Sep;28(3):609-22.

29. Berenson AB, Rickert VI, Grady JJ. A prospective study of the effects of oral and injectable contraception on bone mineral density. Obstet Gynecol 2000;95() 95(4 Suppl 1): S6.

30. 김효민, 한인권, 조남한. 출산 빈도수가 골대사에 미치는 영향: 단면적연구. 대한폐경학회지 1998 Apr;4(1):16-25.

31. Aloia JF, Vaswani AN, Yeh JK, Ross P, Ellis K, Cohn SH. Determinants of bone mass in postmenopausal women. Arch Intern Med 1983 Sep ;143:1700-4.

32. Hreshchyshyn MM, Hopkins A, Zylstra S, Anbar M. Associations of parity, breast-feeding, and birth control pills with lumbar spine and femoral neck bone densities. Am J Obstet Gynecol 1988 Aug;159(2):318-22.