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Full Text: 
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¿µ³²ÀÇ´ëÇмúÁö Vol.24 No.2 p170-178, Dec. 2007
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Original Article
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¼ºÀÎ ±Þ¼º AÇü °£¿° ȯÀÚµéÀÇ ÀÓ»ó ¾ç»ó |
Clinical Characteristics of Adult Patients with Acute Hepatitis A
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ÀºÁ¾·Ä, ÀÌÇåÁÖ, ±èųâ?À庴ÀÍ?¹®ÈñÁ¤
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¿µ³²´ëÇб³ Àǰú´ëÇÐ ³»°úÇб³½Ç
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Ã¥ÀÓÀúÀÚ£ºÀÌÇåÁÖ, ´ë±¸½Ã ³²±¸ ´ë¸í5µ¿ 317-1¹øÁö, ¿µ³²´ëÇб³ Àǰú´ëÇÐ ³»°úÇб³½Ç
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Tel: (053) 620-3830, Fax: (053) 654-8386
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E-mail: hjlee@med.yu.ac.kr
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December 30, 2007
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Abstract
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Background£ºThe incidence of acute hepatitis A in adults has recently been increasing. This study was conducted to investigate the epidemiology and clinical characteristics of acute hepatitis A in Daegu province over the past 10 years.
Materials and Methods£ºWe reviewed the medical records of 55 patients (male/female: 34/21), who were diagnosed with acute hepatitis A by confirmation of the IgM anti-HAV between January 1998 and June 2007.
Results£ºThe mean age was 29.7¡¾10.3 years (range; 17-65 years). The incidence was most common between March and June (56.1%), in the third and fourth decades of life (78.2%) and 90.9% (50/55) of the patients were diagnosed from 2003 to present. The common symptoms included anorexia, nausea or vomiting (69.1%), fever and chills (49.1%), myalgia (47.3%), weight loss (47.3%), fatigue (40.0%), abdominal pain (36.4%), diarrhea (9.1%) and pruritus (5.5%). The mean duration of hospital stay was 8.6¡¾3.4 days (range; 3-20 days). The route of transmission was identified in only 11 patients (20.0%); 7 patients (12.7%) traveled (abroad or domestic), 2 patients (3.6%) ingested raw food and 2 patients (3.6%) had friends with acute hepatitis A. Fifty four patients recovered without complication; one patient developed fulminant hepatitis and recovered after a liver transplantation.
Conclusion£ºThe incidence of acute hepatitis A in adults is increasing. Because of the cost of treatment and potential for serious disease, persons, under 40 are recommened to have hepatitis A vaccination and confirmation of IgG anti-HAV.
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Key Words: Hepatitis A virus, Acute hepatitis A, Clinical features, Vaccination
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