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영남의대학술지 Vol.24_No.2 Suppl. P.S125-131, Dec. 2007
Review
진행 위암의 치료
Treatment of Advanced Gastric Cancer
송선교
영남대학교 의과대학 외과학교실
책임저자：송선교, 대구광역시 남구 대명동 317-1, 영남대학교 의과대학 외과학교실
Tel: (053) 620-3586, Fax: (053) 624-1213
E-mail: sksong@med.yu.ac.kr
December 30, 2007
Abstract
Curative surgery is the most common and desirable treatment for advanced gastric cancer(AGC), but macroscopically curative resection of AGC dose not always mean a curative outcome. For the tailored management of AGC, accurate preoperative stage are made by using abdominal CT, FDG PET and laparoscopy is necessary. In case of T3/T4 lesion, neoadjuvant chemotherapy(NAC) and neoadjuvant chemoradiotherapy(NACR) are effective therapeutic approaches with acceptable toxicity without increasing surgical morbidity and mortality. I recommend the use of a multidisciplinary therapeutic strategy for treatment of AGC. Future applications of newer cytotoxic drugs such as oxaliplatin, capecitabine, irinotecan, and docetaxel or targeted therapies may help to improve the management of AGC.
Key Words: Neoadjuvant chemotherapy, Preoperative staging, Gastric cancer
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